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Wesley Combs

AI Transformation Leader & Futurist

Product • Engineering • Entrepreneurship • Strategy

Equal parts product leader, engineer, entrepreneur, and business strategist. 25+ years driving AI transformation across healthcare, finance, supply chain, and eCommerce. Led NextGen Healthcare to ship the first Ambient AI on mobile EHR. Currently building production AI systems using multi-model LLM pipelines and agentic workflows. Track record includes $76M+ in earned shared savings across two Medicare ACOs, $320M product portfolio leadership, 50+ person technology organizations, and 10 consecutive years of positive ACO performance. I help organizations transform complex workflows with AI that actually ships.

Experience

Founder & Chief ArchitectCurrent

Phiniti.ai / Ambient Scribe

February 2025 – Present
Kingsport, TN

Building AI-powered clinical documentation platform with architecture provisioned for CDS Hooks and real-time decision support.

  • Multi-model LLM pipelines using AWS Bedrock, OpenAI, Claude, and Claude Agent SDK
  • Full-stack development: iOS (SwiftUI), Android (Jetpack Compose), Web (Next.js/TypeScript)
  • Serverless infrastructure design with infrastructure as code
  • FHIR R4 integration via Medplum for EHR data exchange
  • HIPAA-compliant voice agents handling live clinic phone traffic with warm human escalation

Stack: AWS Bedrock, OpenAI, Claude, Serverless, IaC, SwiftUI, Jetpack Compose, TypeScript, FHIR

Chief Information Officer

State of Franklin Healthcare Associates

March 2024 – February 2025
Johnson City, TN

Built the technology organization for a 280-provider, 38-practice ESOP medical group targeting growth to 2,000 providers.

  • Secured $4M infrastructure modernization approval from board
  • Led 1 clinic/month acquisition cadence with data migration and integration
  • Built self-service analytics platform with value-based care dashboards
  • Architected data pipelines for clinical, claims, and operational data

VP, Clinical Solutions

NextGen Healthcare

June 2022 – February 2024
Remote

Led AI-first clinical strategy for $1.8B enterprise (acquired by Thoma Bravo).

  • Shipped first Ambient AI on mobile EHR (November 2023), an industry first
  • Led $320M clinical product portfolio across EHR, Mobile, and clinical content
  • Architected CDS Hooks platform with $182M revenue opportunity
  • Designed FHIR-based strangler fig architecture for legacy modernization
  • Managed cross-functional teams across engineering, product, and data science

CIO & President

Holston Medical Group / OnePartner / ACO Leadership

January 2012 – May 2022
Kingsport, TN

Built and led the healthcare data platforms behind two Medicare ACOs and a nine-state health information exchange.

  • Led 50+ person technology organization; built team now leading at Cerner, Optum, PointClickCare
  • Architected HIE platform serving 3M+ lives across 9 states with 5x ROI; OnePartner has since been acquired by Optum
  • 10 consecutive years of positive ACO performance ($76M+ in earned shared savings)
  • Built data pipelines processing ADT, claims, and clinical data from 100+ practices
  • Negotiated national Allscripts reseller partnership, expanding to new markets

Founder & CEO

Lucent Glow, Inc

2004 – 2011
Kingsport, TN

Healthcare IT pioneer during formative era of health information exchange.

  • Participated in NHIN1/NHIN2 pilots under David Brailer (first National Health IT Coordinator)
  • Built HL7/CCD data interfaces for healthcare interoperability
  • Grew from sole proprietor to 10 employees
  • Successfully exited via sale in 2011

Applications Specialist II

Wellmont Health System / MEDex

2000 – 2004
Kingsport, TN

Entry into healthcare technology on the hospital floor, building the interface work that became a career.

  • HL7 interfaces on Cloverleaf and eGate for lab and clinical integration
  • Claims processing, transcription, patient indexing, and critical care monitoring
  • Authored and sold Ultimate HL7 for .NET, a commercial parsing tool, across several hundred licenses
  • System administration and scripting across AIX, DGUX, and Windows

IT Consultant

Enhanced Systems Consulting

1999 – 2002
Concurrent with Computer Science degree

Client delivery while finishing school, working across eCommerce, banking, and municipal systems.

  • Converted Wideners.com from a FoxPro catalog to SQL Server and Classic ASP e-commerce in 30 to 45 days
  • Moved roughly $1M, about 30% of mail order and call center volume, online in the first year
  • Early loan application workflows against AS/400 financials
  • Content management system used by banks and medical groups

Technical Expertise

AI/ML

AWS BedrockOpenAIClaudeClaude Agent SDKMulti-model LLM PipelinesOn-Device MLAgentic Workflows

Healthcare

FHIR R4HL7v2CDS HooksCMS CCLFHCC Risk AdjustmentValue-Based CareACO Operations

Cloud & DevOps

AWS LambdaCloudFrontAPI GatewayServerlessInfrastructure as CodeEvent-Driven Architecture

Development

TypeScriptSwiftKotlinPythonReact/Next.jsNode.js

EHR Experience

NextGenVeradigm/AllscriptsTouchWorksathenahealthEpicCerner

Education

Executive MBA, Healthcare Leadership

Haslam College of Business, University of Tennessee

2019

B.S. Computer Science

East Tennessee State University

2001

Recognition

2019
Healthcare Hero AwardTri-Cities Business Journal
2015
40 Under 40Tri-Cities Business Journal
2015
Healthcare Heroes Innovation Award
2013
Leadership Kingsport Graduate
2012
Dale Carnegie Graduate

I help organizations transform complex workflows with AI that actually ships.